Tuesday 29 November 2011

The function of the HGF receptor c-Met

 The HGF receptor c-Met is one of great growth- medium product; it is overexpressed in esophageal adenocarcinoma.
The hepatocyte growth factor (HGF) receptor C-Met has established oncogenic properties; However,its expression and function in esophageal adenocarcinoma (EA) remain poorly understood.
We aimed to determine the expression and potential alterations inMet expression in EA. Met expression was investigated in surgical specimens of EA, Barrett's esophagus (BE), and normal esophagus (NE) using immunohistochemistry (IHC) and quantitative reverse transcriptase polymerase chain reaction.
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