Pyrimethamine can inhibit the parasite's dihydrofolate reductase, which interfere with the normal generation of the parasite's folic acid injection, the P. falciparum and P. vivax erythrocyte pre-effective and commonly used for the cause of preventive medicine. In addition, it can inhibit the development of malaria parasites in mosquitoes, it can interrupt transmission. In clinically it is used for the prevention of malaria and telogen anti-relapse treatment.
Pyrimethamine is a white crystalline powder; it is odorless, tasteless. The product is slightly soluble in ethanol or chloroform, almost insoluble in water.
CAS: 58-14-0
Molecular Formula: C12H13ClN4
Molecular Weight: 248.71g/mol
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