HBMEC(Human Brain Microvascular Endothelial Cells) are the main components of blood-brain barrier ,it can limit the soluble substances and cells from the blood into the brain. Brain microvascular endothelial cells and endothelial cells in peripheral compared are with some of the same features. Such as: 1) there are many brain microvascular endothelial cells tight junctions between cells, resulting in a high impedance across the endothelium, the delay cell next to the flux; 2) the lack of brain microvascular endothelial cells, endothelial cells fenestrae structure, the liquid material pinocytosis lower level; 3) brain microvascular endothelial cells and asymmetric positioning of the enzyme-mediated transport system, resulting in "polarization" of the phenotype. With the same peripheral endothelial cells, brain microvascular endothelial cell surface expression of cell adhesion molecules, regulation of white blood cells into the brain. As organ-specific microvascular endothelial cells, endothelial cells normally take from disease research organizations.
more about：buy+HBMEC(Human Brain Microvascular Endothelial Cells)
read more: http://www.growth-medium.com/
No comments:
Post a Comment