Tuesday, 28 February 2012

the descrition of Fumagillin


Fumagillin was originally used against microsporidial parasites Nosema apis and Nosema ceranae infections in honey bees.Fumagillin is also investigated as an inhibitor of malaria parasite growth.Fumagillin has been used in the treatment of microsporidiosis.Fumagillin is also an amebicide.Fumagillin can obstruct blood vessel formation by binding to an enzyme called methionine aminopeptidase 2.As a result, the compound, together with semisynthetic derivatives,are investigated as a angiogenesis inhibitor in the treatment of cancer.

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